Lenvatinib (E7080/MK-7902) in combination with pembrolizumab (MK-3475) vs. standard chemotherapy and lenvatinib monotherapy in participants with recurrent/metastatic head and neck squamous cell carcinoma that progressed after platinum therapy and immunotherapy (MK-7902-009/E7080-G000-228/LEAP-009)

Trial Identifier: 7902-009
Sponsor: MSD
Collaborator:
Eisai Inc.
Start Date: August 2020
Primary Completion Date: May 2024
Study Completion Date: December 2025
Condition: Head and Neck Cancer

Available Languages

For questions about your Trial Results Summary, please see Sponsor contact section within your Trial Results Summary.

Language Description
Protocol Plain Language Summary – English
Protocol Plain Language Summary

Trial Locations

Country Location
Australia, New South Wales Port Macquarie, New South Wales, Australia, 2444
Australia, New South Wales Sydney, New South Wales, Australia, 2148
Australia, Queensland Douglas, Queensland, Australia, 4814
Australia, Queensland Greenslopes, Queensland, Australia, 4120
Australia, South Australia Adelaide, South Australia, Australia, 5000
Australia, Victoria Clayton, Victoria, Australia, 3168
Brazil, Rio Grande do Sul PORTO ALEGRE, Rio Grande do Sul, Brazil, 91350-200
Brazil, Sao Paulo Sao Paulo, Brazil, 01509-010
Canada, AB Calgary, AB, Canada, T2N 4N2
Canada, BC Vancouver, BC, Canada, V5Z 4E6
Canada, ON Hamilton, ON, Canada, L8V 5C2
Canada, ON Toronto, ON, Canada, M4N 3M5
Colombia, Antioquia Medellin, Antioquia, Colombia, 050025
Colombia, Cesar Valledupar, Cesar, Colombia, 200001
Colombia, Cordoba Montería, Cordoba, Colombia, 230002
Colombia, Cundinamarca Bogotá, Cundinamarca, Colombia, 110221
Denmark, Hovedstaden Copenhagen, Hovedstaden, Denmark, 2100
France, Bouches-du-Rhone Marseille, Bouches-du-Rhone, France, 13385
France, Herault Montpellier, Herault, France, 34070
France, Paris Paris, France, 75005
France, Puy-de-Dome Clermont-Ferrand, Puy-de-Dome, France, 63011
France, Seine-Maritime Rouen, Seine-Maritime, France, 76038
France, Val-de-Marne Villejuif, Val-de-Marne, France, 94800
Israel, N/A Be'er Sheva, N/A, Israel, 8400000
Israel, N/A Haifa, N/A, Israel, 3109601
Israel, N/A Jerusalem, N/A, Israel, 9112001
Israel, N/A Ramat Gan, N/A, Israel, 5265601
Korea, Republic of, Kyonggi-do Seongnam, Kyonggi-do, Korea, Republic of, 13620
Korea, Republic of, Kyonggi-do Suwon, Kyonggi-do, Korea, Republic of, 16499
Korea, Republic of, Seoul Seoul, Korea, Republic of, 06351
Korea, Republic of, Seoul Seoul, Korea, Republic of, 03722
Norway, Oslo Oslo, Norway, 0379
Portugal, Porto Porto, Portugal, 4200-072
Portugal, Porto Vila Nova de Gaia, Porto, Portugal, 4434-502
Romania, Bucuresti Bucuresti, Romania, 022548
Romania, Bucuresti București, Bucuresti, Romania, 030171
Romania, Cluj Cluj Napoca, Cluj, Romania, 400015
Romania, Cluj Floresti, Cluj, Romania, 407280
Romania, Dolj Craiova, Dolj, Romania, 200542
Romania, Timis Timișoara, Timis, Romania, 300239
Spain, Barcelona Barcelona, Spain, 08035
Spain, Barcelona Hospitalet de Llobregat, Barcelona, Spain, 08908
Spain, Cataluna Barcelona, Cataluna, Spain, 08036
Spain, Galicia A Coruna, Galicia, Spain, 15009
Spain, Madrid Madrid, Spain, 28034
Spain, Malaga Malaga, Spain, 29010
Spain, Valenciana, Comunitat Valencia, Valenciana, Comunitat, Spain, 46014
Taiwan, Kaohsiung Kaohsiung, Taiwan, 83301
Taiwan, Taichung Taichung, Taiwan, 404332
Taiwan, Taichung Taichung, Taiwan, 407
Taiwan, Tainan Tainan, Taiwan, 70403
Taiwan, Taipei Taipei, Taiwan, 10048
Taiwan, Taipei Taipei, Taiwan, 11217
Taiwan, Taoyuan Taoyuan county, Taoyuan, Taiwan, 333
United Kingdom, Aberdeen City Aberdeen, Aberdeen City, United Kingdom, AB25 2ZN
United Kingdom, East Riding of Yorkshire Cottingham, East Riding of Yorkshire, United Kingdom, HU16 5JQ
United Kingdom, Glasgow City Glasgow, Glasgow City, United Kingdom, G12 0YN
United Kingdom, Great Britain London, Great Britain, United Kingdom, SE1 9RT
United Kingdom, Hampshire Southampton, Hampshire, United Kingdom, SO16 6YD
United Kingdom, London, City of London, London, City of, United Kingdom, W6 8RF
United Kingdom, London, City of London, London, City of, United Kingdom, SW3 6JJ
United Kingdom, Manchester manchester, Manchester, United Kingdom, m20 4bx
United Kingdom, Somerset Taunton, Somerset, United Kingdom, TA1 5DA
United Kingdom, Surrey Sutton, Surrey, United Kingdom, SM2 5PT
United States, CA Duarte, CA, United States, 91010
United States, CA Los Angeles, CA, United States, 90095
United States, CT New Haven, CT, United States, 06510
United States, DC Washington, DC, United States, 20007
United States, FL Gainesville, FL, United States, 32608
United States, FL Orange City, FL, United States, 32763
United States, FL Weston, FL, United States, 33331
United States, GA Augusta, GA, United States, 30912
United States, GA Marietta, GA, United States, 30060
United States, GA Savannah, GA, United States, 31404
United States, IA Iowa City, IA, United States, 52242
United States, ID Post Falls, ID, United States, 83854
United States, IL Chicago, IL, United States, 60607
United States, IL Evanston, IL, United States, 60201
United States, IN Muncie, IN, United States, 47303
United States, KS Westwood, KS, United States, 66205
United States, KY Louisville, KY, United States, 40205
United States, KY Paducah, KY, United States, 42003
United States, LA Baton Rouge, LA, United States, 70808
United States, LA Baton Rouge, LA, United States, 70809
United States, MA Boston, MA, United States, 02118
United States, MA Worcester, MA, United States, 01655
United States, MD Baltimore, MD, United States, 21201
United States, MI Ann Arbor, MI, United States, 48105
United States, MI Detroit, MI, United States, 48201
United States, MI Detroit, MI, United States, 48202
United States, MO St. Louis, MO, United States, 63110
United States, MS Hattiesburg, MS, United States, 39401
United States, MS Jackson, MS, United States, 39202
United States, MT Billings, MT, United States, 59102
United States, NC Charlotte, NC, United States, 28204
United States, NC Durham, NC, United States, 27710
United States, NE Omaha, NE, United States, 68130
United States, NE Omaha, NE, United States, 68105
United States, NJ Hackensack, NJ, United States, 07601
United States, NJ New Brunswick, NJ, United States, 08903
United States, NY Mineola, NY, United States, 11501
United States, NY New York, NY, United States, 10016
United States, OH Cincinnati, OH, United States, 45219
United States, OH Cleveland, OH, United States, 44106
United States, OH Cleveland, OH, United States, 44195
United States, OH Columbus, OH, United States, 43210
United States, OK Tulsa, OK, United States, 74146
United States, PA Gettysburg, PA, United States, 17325
United States, PA Hershey, PA, United States, 17033
United States, PA Philadelphia, PA, United States, 19111
United States, SC Charleston, SC, United States, 29425
United States, SC Greenville, SC, United States, 29607
United States, TX Fort Worth, TX, United States, 76104
United States, UT Salt Lake City, UT, United States, 84106
United States, UT Salt Lake City, UT, United States, 84112
United States, VA Fairfax, VA, United States, 22031-4867
United States, VA Fredericksburg, VA, United States, 22408
United States, WA Tacoma, WA, United States, 98405
United States, WI MILWAUKEE, WI, United States, 53226