A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants with KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

Trial Identifier: 1084-004
Sponsor: MSD
Start Date: May 2024
Primary Completion Date: February 2029
Study Completion Date: February 2031
Condition: Lung Cancer

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Trial Locations

Country Location
Argentina, Buenos Aires CABA, Buenos Aires, Argentina, C1426AGE
Argentina, Buenos Aires CABA, Buenos Aires, Argentina, C1019ABS
Argentina, Buenos Aires Mar del Plata, Buenos Aires, Argentina, B7600FZO
Argentina, Santa Fe Rosario, Santa Fe, Argentina, S2000DSV
Argentina, Santa Fe Rosario, Santa Fe, Argentina, S2000DEJ
Australia, New South Wales Camperdown, New South Wales, Australia, 2050
Australia, Queensland Urraween, Queensland, Australia, 4655
Australia, Victoria Frankston, Victoria, Australia, 3199
Australia, Western Australia Nedlands, Western Australia, Australia, 6009
Austria, Steiermark Graz, Steiermark, Austria, 8036
Austria, Wien Wien, Austria, 1210
Brazil, Minas Gerais Belo Horizonte, Minas Gerais, Brazil, 30380-472
Brazil, Pernambuco Recife, Pernambuco, Brazil, 50040-000
Brazil, Piaui Terezina, Piaui, Brazil, 64049-200
Brazil, Rio de Janeiro Rio de Janeiro, Brazil, 22775-001
Brazil, Rio de Janeiro Rio de Janeiro, Brazil, 20230-130
Brazil, Rio Grande do Norte Natal., Rio Grande do Norte, Brazil, 59062-000
Brazil, Rio Grande do Sul Ijui, Rio Grande do Sul, Brazil, 98700 000
Brazil, Rio Grande do Sul Passo Fundo, Rio Grande do Sul, Brazil, 99010-260
Brazil, Rio Grande do Sul Porto Alegre, Rio Grande do Sul, Brazil, 90050-170
Brazil, Sao Paulo Barretos., Sao Paulo, Brazil, 14784-400
Bulgaria, Pazardzhik Panagyurishte, Pazardzhik, Bulgaria, 4500
Bulgaria, Pleven Pleven, Bulgaria, 5804
Bulgaria, Plovdiv Plovdiv, Bulgaria, 4000
Bulgaria, Plovdiv Plovdiv, Bulgaria, 4004
Bulgaria, Sofia (stolitsa) Sofia, Sofia (stolitsa), Bulgaria, 1632
Canada, MB Winnipeg, MB, Canada, R3E 0V9
Canada, NS Halifax, NS, Canada, B3H 2Y9
Canada, ON Hamilton, ON, Canada, L8V 5C2
Canada, ON Toronto, ON, Canada, M4N 3M5
Canada, QC Montreal, QC, Canada, H3T 1M5
Canada, QC Trois-Rivières, QC, Canada, G8Z 3R9
Chile, Maule Talca, Maule, Chile, 3465584
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 7500921
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 7560908
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 8420383
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 7500713
China, Anhui Hefei, Anhui, China, 230031
China, Beijing Beijing, China, 100730
China, Beijing Beijing, China, 101149
China, Beijing Beijing, China, 100142
China, Chongqing Chongqing, China, 400042
China, Chongqing Chongqing, China, 400030
China, Fujian Fuzhou, Fujian, China, 350014
China, Fujian Xiamen, Fujian, China, 361003
China, Guangdong Guangzhou, Guangdong, China, 510160
China, Guangdong Guangzhou, Guangdong, China, 510515
China, Guangdong Guangzhou, Guangdong, China, 510555
China, Heilongjiang Harbin, Heilongjiang, China, 150081
China, Heilongjiang Jiamusi, Heilongjiang, China, 154007
China, Henan Zhengzhou, Henan, China, 450008
China, Hubei Wuhan, Hubei, China, 430000
China, Hubei Wuhan, Hubei, China, 430079
China, Hunan Changsha, Hunan, China, 410013
China, Hunan Changsha, Hunan, China, 410011
China, Jiangsu Nanjing, Jiangsu, China, 210008
China, Jiangsu Nanjing, Jiangsu, China, 210012
China, Jiangsu Suzhou, Jiangsu, China, 215006
China, Jiangsu Wuxi City, Jiangsu, China, 214122
China, Jiangxi Nanchang, Jiangxi, China, 330209
China, Jiangxi Nanchang, Jiangxi, China, 330000
China, Jilin Changchun, Jilin, China, 130000
China, Shaanxi Xian, Shaanxi, China, 710000
China, Shandong Jinan, Shandong, China, 250117
China, Shandong Linyi, Shandong, China, 276001
China, Shanghai Shanghai, China, 200030
China, Shanghai Shanghai, China, 200032
China, Shanxi Taiyuan, Shanxi, China, 030000
China, Shanxi Xian, Shanxi, China, 710038
China, Sichuan Cheng Du, Sichuan, China, 610000
China, Sichuan chengdu, Sichuan, China, 610042
China, Sichuan Chengdu, Sichuan, China, 610031
China, Sichuan Neijiang, Sichuan, China, 641000
China, Xinjiang Urumqi, Xinjiang, China, 830000
China, Yunnan Kunming, Yunnan, China, 650107
China, Zhejiang hangzhou, Zhejiang, China, 310006
China, Zhejiang Hangzhou, Zhejiang, China, 310016
China, Zhejiang Linhai, Zhejiang, China, 317000
China, Zhejiang Wenzhou, Zhejiang, China, 325015
France, Bourgogne Dijon, Bourgogne, France, 21000
France, Gard Nimes, Gard, France, 30029
France, Ile-de-France Boulogne-Billancourt, Ile-de-France, France, 92100
France, Nord Valenciennes, Nord, France, 59304
France, Puy-de-Dome Clermont-Ferrand, Puy-de-Dome, France, 63003
France, Vaucluse Avignon, Vaucluse, France, 84000
Georgia, Ajaria Batumi, Ajaria, Georgia, 6000
Georgia, Ajaria Tbilisi, Ajaria, Georgia, 0186
Georgia, Tbilisi Tbilisi, Georgia, 0112
Georgia, Tbilisi Tbilisi, Georgia, 0177
Georgia, Tbilisi Tbilisi, Georgia, 1206
Georgia, Tbilisi Tbilisi, Georgia, 0162
Georgia, Tbilisi Tbilisi, Georgia, 0144
Georgia, Tbilisi Tbilisi, Georgia, 0102
Germany, Baden-Wurttemberg Stuttgart, Baden-Wurttemberg, Germany, 70199
Germany, Nordrhein-Westfalen Bielefeld, Nordrhein-Westfalen, Germany, 33611
Germany, Nordrhein-Westfalen Solingen, Nordrhein-Westfalen, Germany, 42699
Greece, Achaia PATRAS, Achaia, Greece, 26504
Greece, Attiki Athens, Attiki, Greece, 115 27
Greece, Attiki ATHENS, Attiki, Greece, 115 22
Greece, Attiki Marousi, Attiki, Greece, 151 25
Greece, Thessalia Larissa, Thessalia, Greece, 411 10
Greece, Thessaloniki Thessaloniki, Greece, 570 10
Greece, Thessaloniki Thessaloniki, Greece, 552 36
India, Delhi New Delhi, Delhi, India, 110029
India, Delhi New Delhi, Delhi, India, 110076
India, Maharashtra Mumbai, Maharashtra, India, 400004
India, Maharashtra Mumbai, Maharashtra, India, 400012
Italy, Campania Napoli, Campania, Italy, 80131
Italy, Emilia-Romagna Ravenna, Emilia-Romagna, Italy, 48121
Italy, Friuli-Venezia Giulia Aviano, Friuli-Venezia Giulia, Italy, 33081
Italy, Lazio Roma, Lazio, Italy, 00168
Italy, Lombardia Milan, Lombardia, Italy, 20133
Italy, Lombardia Milano, Lombardia, Italy, 20141
Italy, Napoli Naples, Napoli, Italy, 80131
Italy, Padova Padova, Italy, 35131
Italy, Roma Rome, Roma, Italy, 00144
Italy, Toscana Livorno, Toscana, Italy, 57124
Japan, Aichi Nagoya, Aichi, Japan, 466-8560
Japan, Aichi Toyoake, Aichi, Japan, 470-1192
Japan, Chiba Chiba, Japan, 260-8677
Japan, Chiba Kashiwa, Chiba, Japan, 277-8577
Japan, Ehime Matsuyam, Ehime, Japan, 719-0280
Japan, Fukuoka Fukuoka,, Fukuoka, Japan, 811-1395
Japan, Fukuoka Kurume, Fukuoka, Japan, 830-0011
Japan, Gunma Ota, Gunma, Japan, 373-8550
Japan, Hiroshima Hiroshima, Japan, 730-8518
Japan, Hokkaido Sapporo, Hokkaido, Japan, 060-8543
Japan, Ishikawa Kanazawa, Ishikawa, Japan, 920-8641
Japan, Kanagawa kawasaki, Kanagawa, Japan, 216-8511
Japan, Kumamoto Kumamoto, Japan, 861-4193
Japan, Mie Matsusaka, Mie, Japan, 515-8544
Japan, Miyagi Natori, Miyagi, Japan, 981-1293
Japan, Miyagi Sendai, Miyagi, Japan, 981-0914
Japan, Niigata Niigata, Japan, 951-8520
Japan, Osaka Hirakata, Osaka, Japan, 573-1191
Japan, Osaka Osaka, Japan, 545-8586
Japan, Osaka Takatsuki, Osaka, Japan, 569-8686
Japan, Saitama Kitaadachi-gun, Saitama, Japan, 362-0806
Japan, Tokyo Bunkyo, Tokyo, Japan, 113-8603
Japan, Tokyo Ota, Tokyo, Japan, 143-8541
Japan, Tokyo Shinjuku, Tokyo, Japan, 160-0023
Japan, Tokyo Shinjuku, Tokyo, Japan, 162-8655
Korea, Republic of, Incheon Bupyeong-gu, Incheon, Korea, Republic of, 21431
Korea, Republic of, Incheon Incheon, Korea, Republic of, 22332
Korea, Republic of, Jeonranamdo Hwasun, Jeonranamdo, Korea, Republic of, 58128
Korea, Republic of, Kyonggi-do Suwon-si, Kyonggi-do, Korea, Republic of, 16247
Korea, Republic of, Kyongsangnam-do Yangsan, Kyongsangnam-do, Korea, Republic of, 50612
Korea, Republic of, Seoul Seoul, Korea, Republic of, 08308
Korea, Republic of, Seoul Seoul, Korea, Republic of, 02447
Korea, Republic of, Seoul Seoul, Korea, Republic of, 03312
Korea, Republic of, Seoul Seoul, Korea, Republic of, 02841
Korea, Republic of, Taegu-Kwangyokshi Daegu, Taegu-Kwangyokshi, Korea, Republic of, 42601
Korea, Republic of, Taegu-Kwangyokshi Daegu, Taegu-Kwangyokshi, Korea, Republic of, 42415
Korea, Republic of, Taejon-Kwangyokshi Jung-gu, Taejon-Kwangyokshi, Korea, Republic of, 35015
Mexico, Distrito Federal Mexico, Distrito Federal, Mexico, 06700
Mexico, Nuevo Leon Monterrey, Nuevo Leon, Mexico, 66460
Mexico, Oaxaca Oaxaca, Mexico, 68000
Netherlands, Gelderland Ede, Gelderland, Netherlands, 6716 RP
Netherlands, Gelderland Harderwijk, Gelderland, Netherlands, 3844 DG
Netherlands, Overijssel Zwolle, Overijssel, Netherlands, 8025 AB
Netherlands, Utrecht Utrecht, Netherlands, 3584 CX
New Zealand, Auckland Auckland, New Zealand, 1023
Philippines, National Capital Region Pasig, National Capital Region, Philippines, 1600
Philippines, National Capital Region Quezon City, National Capital Region, Philippines, 1100
Philippines, National Capital Region QUEZON CITY, National Capital Region, Philippines, 1102
Poland, Lubelskie Lublin, Lubelskie, Poland, 20-090
Poland, Malopolskie Gorlice, Malopolskie, Poland, 38-300
Poland, Malopolskie Krakow, Malopolskie, Poland, 30-727
Poland, Mazowieckie Warszawa, Mazowieckie, Poland, 02-781
Poland, Podkarpackie Przemysl, Podkarpackie, Poland, 37-700
Poland, Warminsko-mazurskie Olsztyn, Warminsko-mazurskie, Poland, 10-357
Romania, Brasov Brasov, Romania, 500052
Romania, Bucuresti Bucharest, Bucuresti, Romania, 020335
Romania, Cluj Cluj, Romania, 400015
Romania, Dolj Craiova, Dolj, Romania, 200542
Romania, Suceava Suceava, Romania, 720214
Romania, Timis Timișoara, Timis, Romania, 300239
Spain, Barcelona Barcelona, Spain, 08035
Spain, Las Palmas Las Palmas de Gran Canaria, Las Palmas, Spain, 35001
Spain, Madrid Madrid, Spain, 28040
Spain, Madrid Madrid, Spain, 28006
Spain, Madrid, Comunidad de Madrid, Madrid, Comunidad de, Spain, 28009
Spain, Malaga Malaga, Spain, 29010
Spain, Malaga Málaga, Malaga, Spain, 29011
Spain, Sevilla Sevilla, Spain, 41009
Turkey, Adana Adana, Turkey, 01140
Turkey, Ankara Ankara, Turkey, 06800
Turkey, Ankara Ankara, Turkey, 06010
Turkey, Ankara Ankara, Turkey, 06230
Turkey, Ankara Ankara, Turkey, 06520
Turkey, Istanbul Istanbul, Turkey, 34722
Turkey, Istanbul Istanbul, Turkey, 34214
Turkey, Izmir Bornova, Izmir, Turkey, 35100
Ukraine, Cherkaska oblast Cherkasy, Cherkaska oblast, Ukraine, 18009
Ukraine, Chernivetska oblast Chernivtsi, Chernivetska oblast, Ukraine, 58013
Ukraine, Dnipropetrovska oblast Kryvyi Rih, Dnipropetrovska oblast, Ukraine, 50000
Ukraine, Ivano-Frankivska oblast Ivano-Frankivsk, Ivano-Frankivska oblast, Ukraine, 76018
Ukraine, Kirovohradska oblast Kropyvnytskyi, Kirovohradska oblast, Ukraine, 25011
Ukraine, Kyivska oblast Kiev, Kyivska oblast, Ukraine, 03022
Ukraine, Lvivska oblast Lviv, Lvivska oblast, Ukraine, 79059
Ukraine, Rivnenska oblast Rivne, Rivnenska oblast, Ukraine, 33007
Ukraine, Rivnenska oblast Rivne, Rivnenska oblast, Ukraine, 33010
Ukraine, Vinnytska oblast Vinnytsia, Vinnytska oblast, Ukraine, 21029
Ukraine, Volynska oblast Lutsk, Volynska oblast, Ukraine, 43018
United Kingdom, Buckinghamshire Milton Keynes, Buckinghamshire, United Kingdom, MK6 5LD
United Kingdom, Devon Exeter, Devon, United Kingdom, EX2 5DW
United States, CA Bakersfield, CA, United States, 93309
United States, CA Beverly Hills, CA, United States, 90211
United States, CT Stamford, CT, United States, 06902
United States, FL Miami Beach, FL, United States, 33140
United States, IL Skokie, IL, United States, 60077
United States, MO Kansas City, MO, United States, 64108
United States, MO Springfield, MO, United States, 65807
United States, MT Billings, MT, United States, 59102
United States, NJ Morristown, NJ, United States, 07960
United States, NY Albany, NY, United States, 12206
United States, OH Cincinnati, OH, United States, 45219
United States, OH Kettering, OH, United States, 45429
United States, PA Lancaster, PA, United States, 17601
United States, TX Houston, TX, United States, 77030
United States, WI Madison, WI, United States, 53715