A Study of MK-1084 Plus Pembrolizumab (MK-3475) in Participants with KRAS G12C Mutant, Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004)

Trial Identifier: 1084-004
Sponsor: MSD
Start Date: May 2024
Primary Completion Date: February 2029
Study Completion Date: February 2031
Condition: Lung Cancer

Available Languages

For questions about your Trial Results Summary, please see Sponsor contact section within your Trial Results Summary.

Language Description
Protocol Plain Language Summary – English

Trial Locations

Country Location
Argentina, Buenos Aires CABA, Buenos Aires, Argentina, C1426AGE
Argentina, Buenos Aires CABA, Buenos Aires, Argentina, C1019ABS
Argentina, Buenos Aires Mar del Plata, Buenos Aires, Argentina, B7600FZO
Argentina, Santa Fe Rosario, Santa Fe, Argentina, S2000DSV
Argentina, Santa Fe Rosario, Santa Fe, Argentina, S2000DEJ
Australia, Victoria Frankston, Victoria, Australia, 3199
Australia, Western Australia Nedlands, Western Australia, Australia, 6009
Brazil, Minas Gerais Belo Horizonte, Minas Gerais, Brazil, 30380-472
Brazil, Pernambuco Recife, Pernambuco, Brazil, 50040-000
Brazil, Piaui Terezina, Piaui, Brazil, 64049-200
Brazil, Rio de Janeiro Rio de Janeiro, Brazil, 22775-001
Brazil, Rio Grande do Norte Natal, Rio Grande do Norte, Brazil, 59062-000
Brazil, Rio Grande do Sul Porto Alegre, Rio Grande do Sul, Brazil, 90050-170
Brazil, Sao Paulo Barretos, Sao Paulo, Brazil, 14784-400
Chile, Maule Talca, Maule, Chile, 3465584
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 7500921
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 7560908
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 8420383
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 7500713
China, Anhui Hefei, Anhui, China, 230000
China, Beijing Beijing, China, 100730
China, Beijing Beijing, China, 101149
China, Beijing Beijing, China, 100142
China, Chongqing Chongqing, China, 400042
China, Chongqing Chongqing, China, 400030
China, Fujian Fuzhou, Fujian, China, 350014
China, Guangdong Guangzhou, Guangdong, China, 510160
China, Guangdong Guangzhou, Guangdong, China, 510515
China, Guangdong Guangzhou, Guangdong, China, 510555
China, Heilongjiang Jiamusi, Heilongjiang, China, 154007
China, Henan Zhengzhou, Henan, China, 450008
China, Hubei Wuhan, Hubei, China, 430000
China, Hubei Wuhan, Hubei, China, 430079
China, Hunan Changsha, Hunan, China, 410013
China, Hunan Changsha, Hunan, China, 410011
China, Jiangsu Nanjing, Jiangsu, China, 210012
China, Jiangsu NanJing, Jiangsu, China, 210008
China, Jiangsu Suzhou, Jiangsu, China, 215006
China, Jiangsu Wuxi City, Jiangsu, China, 214122
China, Jiangxi Nanchang, Jiangxi, China, 330209
China, Jiangxi Nanchang, Jiangxi, China, 330000
China, Jilin Changchun, Jilin, China, 130000
China, Shaanxi Xian, Shaanxi, China, 710000
China, Shandong Linyi, Shandong, China, 276001
China, Shanghai Shanghai, China, 200030
China, Shanghai Shanghai, China, 200032
China, Shanxi Xian, Shanxi, China, 710038
China, Sichuan Cheng Du, Sichuan, China, 610041
China, Sichuan chengdu, Sichuan, China, 610042
China, Sichuan Chengdu, Sichuan, China, 610031
China, Sichuan Neijiang, Sichuan, China, 641199
China, Xinjiang Urumqi, Xinjiang, China, 830000
China, Yunnan Kunming, Yunnan, China, 650118
China, Zhejiang hangzhou, Zhejiang, China, 310003
China, Zhejiang Hangzhou, Zhejiang, China, 310016
China, Zhejiang Linhai, Zhejiang, China, 317000
China, Zhejiang Wenzhou, Zhejiang, China, 325015
Japan, Ehime Matsuyam, Ehime, Japan, 719-0280
Japan, Fukuoka Fukuoka,, Fukuoka, Japan, 811-1395
Japan, Fukuoka Kurume, Fukuoka, Japan, 830-0011
Japan, Gunma Ota, Gunma, Japan, 373-8550
Japan, Hiroshima Hiroshima, Japan, 730-8518
Japan, Ishikawa Kanazawa, Ishikawa, Japan, 920-8641
Japan, Kanagawa kawasaki, Kanagawa, Japan, 216-8511
Japan, Kumamoto Kumamoto, Japan, 861-4193
Japan, Mie Matsusaka, Mie, Japan, 515-8544
Japan, Miyagi Natori, Miyagi, Japan, 981-1293
Japan, Miyagi Sendai, Miyagi, Japan, 981-0914
Japan, Osaka Hirakata, Osaka, Japan, 573-1191
Japan, Osaka Osaka, Japan, 545-8586
Japan, Osaka Takatsuki, Osaka, Japan, 569-8686
Japan, Tokyo Bunkyo, Tokyo, Japan, 113-8603
Japan, Tokyo Shinjuku, Tokyo, Japan, 160-0023
Japan, Tokyo Shinjuku, Tokyo, Japan, 162-8655
Korea, Republic of, Incheon Bupyeong-gu, Incheon, Korea, Republic of, 21431
Korea, Republic of, Jeonranamdo Hwasun, Jeonranamdo, Korea, Republic of, 58128
Korea, Republic of, Kyonggi-do Suwon-si, Kyonggi-do, Korea, Republic of, 16247
Korea, Republic of, Kyongsangnam-do Yangsan, Kyongsangnam-do, Korea, Republic of, 50612
Korea, Republic of, Seoul Seoul, Korea, Republic of, 08308
Korea, Republic of, Seoul Seoul, Korea, Republic of, 02447
Korea, Republic of, Taejon-Kwangyokshi Jung-gu, Taejon-Kwangyokshi, Korea, Republic of, 35015
Netherlands, Gelderland Harderwijk, Gelderland, Netherlands, 3844 DG
Netherlands, Overijssel Zwolle, Overijssel, Netherlands, 8025 AB
Netherlands, Utrecht Utrecht, Netherlands, 3584 CX
New Zealand, Auckland Auckland, New Zealand, 1023
Romania, Brasov Brasov, Romania, 500052
Romania, Cluj Cluj, Romania, 400015
Romania, Dolj Craiova, Dolj, Romania, 200542
Romania, Suceava Suceava, Romania, 720214
Romania, Timis Timișoara, Timis, Romania, 300239
Spain, Barcelona Barcelona, Spain, 08035
Spain, Madrid Madrid, Spain, 28040
Spain, Malaga Málaga, Malaga, Spain, 29011
Spain, Sevilla Sevilla, Spain, 41009
Ukraine, Cherkaska oblast Cherkasy, Cherkaska oblast, Ukraine, 18009
Ukraine, Chernivetska oblast Chernivtsi, Chernivetska oblast, Ukraine, 58013
Ukraine, Dnipropetrovska oblast Kryvyi Rih, Dnipropetrovska oblast, Ukraine, 50000
Ukraine, Ivano-Frankivska oblast Ivano-Frankivsk, Ivano-Frankivska oblast, Ukraine, 76018
Ukraine, Kirovohradska oblast Kropyvnytskyi, Kirovohradska oblast, Ukraine, 25011
Ukraine, Kyivska oblast Kiev, Kyivska oblast, Ukraine, 03022
Ukraine, Lvivska oblast Lviv, Lvivska oblast, Ukraine, 79000
Ukraine, Rivnenska oblast Rivne, Rivnenska oblast, Ukraine, 33007
Ukraine, Vinnytska oblast Vinnytsia, Vinnytska oblast, Ukraine, 21029
Ukraine, Volynska oblast Lutsk, Volynska oblast, Ukraine, 43018
United States, CA Beverly Hills, CA, United States, 90211
United States, IL Skokie, IL, United States, 60077
United States, MT Billings, MT, United States, 59102
United States, OH Cincinnati, OH, United States, 45219
United States, OH Kettering, OH, United States, 45429
United States, TX Houston, TX, United States, 77030
United States, WI Madison, WI, United States, 53715