Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women with BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK-001/ENGOT-ov43/GOG-3036)

Trial Identifier: 7339-001
Sponsor: MSD
Collaborator:
ENGOT
Gynecologic Oncology Group
Start Date: December 2018
Primary Completion Date: August 2024
Study Completion Date: May 2026
Condition: Ovarian Cancer; Cancer - Other

Available Languages

For questions about your Trial Results Summary, please see Sponsor contact section within your Trial Results Summary.

Language Description
Protocol Plain Language Summary – English

Trial Locations

Country Location
Australia, New South Wales Kogarah, New South Wales, Australia, 2217
Australia, Queensland Cairns, Queensland, Australia, 4870
Australia, Victoria Ballarat, Victoria, Australia, 3350
Australia, Victoria Clayton, Victoria, Australia, 3168
Australia, Victoria St Albans, Victoria, Australia, 3021
Belgium, Antwerpen Bonheiden, Antwerpen, Belgium, 1932
Belgium, Antwerpen Leuven, Antwerpen, Belgium, 3000
Belgium, Bruxelles-Capitale, Region de Brussels, Bruxelles-Capitale, Region de, Belgium, 1200
Belgium, Hainaut Charleroi, Hainaut, Belgium, 6000
Belgium, Liege Liège, Liege, Belgium, 4000
Belgium, Limburg Hasselt, Limburg, Belgium, 3500
Belgium, Luxembourg Libramont, Luxembourg, Belgium, 6800
Belgium, Oost-Vlaanderen Gent, Oost-Vlaanderen, Belgium, 9000
Brazil, Ceara Fortaleza, Ceara, Brazil, 60430-230
Brazil, Goias Goiania, Goias, Brazil, 74605-070
Brazil, Parana Curitiba, Parana, Brazil, 82520-060
Brazil, Rio de Janeiro Rio de Janeiro, Brazil, 20220-410
Brazil, Rio Grande do Sul Ijui, Rio Grande do Sul, Brazil, 98700-000
Brazil, Rio Grande do Sul Lajeado, Rio Grande do Sul, Brazil, 95900-000
Brazil, Rio Grande do Sul Porto Alegre, Rio Grande do Sul, Brazil, 91350-200
Brazil, Sao Paulo Sao Paulo, Brazil, 01317-000
Brazil, Sao Paulo Sao Paulo, Brazil, 01246-000
Brazil, Sao Paulo Sao Paulo, Brazil, 01321-001
Canada, AB Calgary, AB, Canada, T2N 4N2
Canada, ON Kingston, ON, Canada, K7L 2V7
Canada, ON Mississauga, ON, Canada, L5M 2N1
Canada, ON Toronto, ON, Canada, M5G 2M9
Canada, QC Chicoutimi, QC, Canada, G7H 5H6
Canada, QC Montreal, QC, Canada, H2X 0A9
Canada, QC Montreal, QC, Canada, H1T 2M4
Canada, QC MONTREAL, QC, Canada, H4A 3J1
Chile, Antofagasta Antofagasta, Chile, 1240000
Chile, Araucania Temuco, Araucania, Chile, 4810218
Chile, Araucania Temuco, Araucania, Chile, 4780000
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 8330032
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 7510032
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 7630370
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 7500922
Chile, Valparaiso Vina del Mar, Valparaiso, Chile, 2520598
Colombia, Atlantico Barranquilla, Atlantico, Colombia, 080002
Colombia, Cesar Valledupar, Cesar, Colombia, 200001
Colombia, Cordoba Monteria, Cordoba, Colombia, 230002
Colombia, Distrito Capital de Bogota Bogota, Distrito Capital de Bogota, Colombia, 110321
Colombia, Distrito Capital de Bogota Bogota, Distrito Capital de Bogota, Colombia, 111321
Colombia, Valle del Cauca Cali, Valle del Cauca, Colombia, 760042
Czech Republic, Brno-mesto Brno, Brno-mesto, Czech Republic, 602 00
Czech Republic, Moravskoslezsky kraj Ostrava-Poruba, Moravskoslezsky kraj, Czech Republic, 708 52
Czech Republic, Olomouc Olomouc, Czech Republic, 779 00
Czech Republic, Praha, hlavni mesto Praha, Praha, hlavni mesto, Czech Republic, 120 00
Czech Republic, Praha, hlavni mesto Praha, Praha, hlavni mesto, Czech Republic, 180 81
France, Auvergne Lyon, Auvergne, France, 69008
France, Bas-Rhin Strasbourg, Bas-Rhin, France, 67065
France, Bouches-du-Rhone Marseille, Bouches-du-Rhone, France, 13005
France, Bretagne Brest, Bretagne, France, 29200
France, Gard Nimes, Gard, France, 30029
France, Loire Saint-Priest-en-Jarez, Loire, France, 42270
France, Meurthe-et-Moselle Nancy, Meurthe-et-Moselle, France, 54100
France, Paris Paris, France, 75020
France, Val-de-Marne Villejuif, Val-de-Marne, France, 94800
Germany, Baden-Wurttemberg Stuttgart, Baden-Wurttemberg, Germany, 70199
Germany, Bayern Muenchen, Bayern, Germany, 72074
Germany, Berlin Berlin, Germany, 13353
Germany, Nordrhein-Westfalen Aachen, Nordrhein-Westfalen, Germany, 52074
Germany, Nordrhein-Westfalen Bonn, Nordrhein-Westfalen, Germany, 53111
Germany, Nordrhein-Westfalen Dortmund, Nordrhein-Westfalen, Germany, 44137
Germany, Nordrhein-Westfalen Duesseldorf, Nordrhein-Westfalen, Germany, 40225
Germany, Nordrhein-Westfalen Krefeld, Nordrhein-Westfalen, Germany, 47805
Germany, Nordrhein-Westfalen Muenster, Nordrhein-Westfalen, Germany, 48149
Germany, Saarland Saarbruecken, Saarland, Germany, 66113
Germany, Sachsen Chemnitz, Sachsen, Germany, 09116
Germany, Schleswig-Holstein Kiel, Schleswig-Holstein, Germany, 24116
Hungary, Baranya Pecs, Baranya, Hungary, 7624
Hungary, Borsod-Abauj-Zemplen Miskolc, Borsod-Abauj-Zemplen, Hungary, 1051
Hungary, Budapest Budapest, Hungary, 1122
Hungary, Budapest Budapest, Hungary, 1145
Hungary, Debrecen Debrecen, Hungary, 4032
Israel, N/A Beer-Sheva, N/A, Israel, 8410101
Israel, N/A Hadera, N/A, Israel, 3810101
Israel, N/A Haifa, N/A, Israel, 3525408
Israel, N/A Haifa, N/A, Israel, 3436212
Israel, N/A Holon, N/A, Israel, 5822012
Israel, N/A Jerusalem, N/A, Israel, 9103102
Israel, N/A Petah Tikva, N/A, Israel, 4941492
Israel, N/A Ramat Gan, N/A, Israel, 5262000
Israel, N/A Tel Aviv, N/A, Israel, 6423906
Italy, Abruzzo Bari, Abruzzo, Italy, 70124
Italy, Benevento Benevento, Italy, 82100
Italy, Catania Catania, Italy, 95126
Italy, Lecco Lecco, Italy, 23900
Italy, Lombardia Milano, Lombardia, Italy, 20141
Italy, Milano Milano, Italy, 20133
Italy, Napoli Napoli, Italy, 80131
Italy, Piemonte Torino, Piemonte, Italy, 10126
Italy, Roma Roma, Italy, 00168
Italy, Roma Roma, Italy, 00161
Italy, Trento Trento, Italy, 38122
Italy, Udine Udine, Italy, 33100
Italy, Veneto Padova, Veneto, Italy, 35128
Japan, Chiba Kashiwa, Chiba, Japan, 277-8577
Japan, Ehime Matsuyama, Ehime, Japan, 791-0280
Japan, Ehime Toon, Ehime, Japan, 791-0295
Japan, Gunma Ota, Gunma, Japan, 373-8550
Japan, Hokkaido Sapporo, Hokkaido, Japan, 060-8648
Japan, Iwate Shiwa-gun, Iwate, Japan, 028-3695
Japan, Kagoshima Kagoshima, Japan, 890-8760
Japan, Kanagawa Kawasaki, Kanagawa, Japan, 216-8511
Japan, Niigata Niigata, Japan, 951-8566
Japan, Okinawa Nakagami-gun, Okinawa, Japan, 903-0215
Japan, Osaka Osaka, Japan, 541-8567
Japan, Saitama Hidaka, Saitama, Japan, 350-1298
Japan, Saitama Kitaadachi-gun, Saitama, Japan, 362-0806
Japan, Saitama Tokorozawa, Saitama, Japan, 359-8513
Japan, Tokyo Mitaka, Tokyo, Japan, 181-8611
Japan, Tokyo Tokyo, Japan, 104-0045
Korea, Republic of, Kyonggi-do Seongnam-si, Kyonggi-do, Korea, Republic of, 13620
Korea, Republic of, Seoul Seoul, Korea, Republic of, 03722
Korea, Republic of, Seoul Seoul, Korea, Republic of, 06351
Korea, Republic of, Seoul Seoul, Korea, Republic of, 05505
Korea, Republic of, Seoul Seoul, Korea, Republic of, 03080
Poland, Mazowieckie Warszawa, Mazowieckie, Poland, 02-781
Poland, Podlaskie Bialystok, Podlaskie, Poland, 15-027
Poland, Pomorskie Gdynia, Pomorskie, Poland, 81-519
Poland, Slaskie Gliwice, Slaskie, Poland, 44-102
Poland, Swietokrzyskie Kielce, Swietokrzyskie, Poland, 25-734
Poland, Wielkopolskie Poznan, Wielkopolskie, Poland, 61-848
Russian Federation, Arkhangel skaya oblast Arkhangelsk, Arkhangel skaya oblast, Russian Federation, 163045
Russian Federation, Baskortostan, Respublika Ufa, Baskortostan, Respublika, Russian Federation, 450054
Russian Federation, Kaluzskaja oblast Obninsk, Kaluzskaja oblast, Russian Federation, 249036
Russian Federation, Moskva Moscow, Moskva, Russian Federation, 115478
Russian Federation, Moskva Moscow, Moskva, Russian Federation, 125367
Russian Federation, Moskva Moscow, Moskva, Russian Federation, 115682
Russian Federation, Sankt-Peterburg Saint Petersburg, Sankt-Peterburg, Russian Federation, 198255
Russian Federation, Sankt-Peterburg Saint-Petersburg, Sankt-Peterburg, Russian Federation, 197758
Russian Federation, Tatarstan, Respublika Kazan, Tatarstan, Respublika, Russian Federation, 420029
South Africa, Eastern Cape Port Elizabeth, Eastern Cape, South Africa, 6045
South Africa, Gauteng Cape Town, Gauteng, South Africa, 7925
South Africa, Gauteng Johannesburg, Gauteng, South Africa, 2193
South Africa, Gauteng Pretoria, Gauteng, South Africa, 0081
South Africa, Gauteng Pretoria, Gauteng, South Africa, 0181
South Africa, Gauteng Pretoria, Gauteng, South Africa, 0002
South Africa, Gauteng Pretoria, Gauteng, South Africa, 0031
South Africa, Gauteng Sandton, Gauteng, South Africa, 2196
South Africa, Kwazulu-Natal Durban, Kwazulu-Natal, South Africa, 4091
South Africa, Western Cape Cape Town, Western Cape, South Africa, 7700
South Africa, Western Cape George, Western Cape, South Africa, 6530
South Africa, Western Cape Kraaifontein, Western Cape, South Africa, 7570
Spain, Barcelona Hospitalet de Llobregat, Barcelona, Spain, 08909
Spain, Barcelona Manresa, Barcelona, Spain, 08243
Spain, Barcelona Terrassa, Barcelona, Spain, 08227
Spain, Caceres Caceres, Spain, 10003
Spain, Gipuzkoa Donostia, Gipuzkoa, Spain, 20014
Spain, La Coruna A Coruna, La Coruna, Spain, 15006
Spain, Lugo Lugo, Spain, 27003
Spain, Madrid Madrid, Spain, 28027
Spain, Sevilla Sevilla, Spain, 41013
Spain, Valenciana, Comunitat Valencia, Valenciana, Comunitat, Spain, 46009
Spain, Valenciana, Comunitat Valencia, Valenciana, Comunitat, Spain, 46014
Taiwan, Changhua Changhua, Taiwan, 50006
Taiwan, Taichung Taichung, Taiwan, 40705
Taiwan, Taichung Taichung, Taiwan, 40447
Taiwan, Tainan Tainan, Taiwan, 704
Taiwan, Taipei Taipei, Taiwan, 10002
Taiwan, Taipei Taipei, Taiwan, 11217
Taiwan, Taipei Taipei, Taiwan, 10449
Taiwan, Taoyuan Taoyuan, Taiwan, 333
Turkey, Ankara Ankara, Turkey, 06590
Turkey, Ankara Ankara, Turkey, 06050
Turkey, Antalya Antalya, Turkey, 07070
Turkey, Bursa Bursa, Turkey, 16059
Turkey, Istanbul Istanbul, Turkey, 34093
Turkey, Istanbul Istanbul, Turkey, 34147
Turkey, Istanbul Istanbul, Turkey, 34214
Turkey, Istanbul Kucukcekmece, Istanbul, Turkey, 34303
Turkey, Sakarya Sakarya, Turkey, 54290
Ukraine, Ivano-Frankivska oblast Ivano-Frankivsk, Ivano-Frankivska oblast, Ukraine, 76018
Ukraine, Kharkivska oblast Kharkiv, Kharkivska oblast, Ukraine, 61024
Ukraine, Khmelnytska oblast Khmelnytskyi, Khmelnytska oblast, Ukraine, 29009
Ukraine, Kyiv Kyiv, Ukraine, 03115
Ukraine, Lvivska oblast Lviv, Lvivska oblast, Ukraine, 79031
Ukraine, Odeska oblast Odesa, Odeska oblast, Ukraine, 65055
Ukraine, Sumska oblast Sumy, Sumska oblast, Ukraine, 40022
Ukraine, Zakarpatska oblast Uzhgorod, Zakarpatska oblast, Ukraine, 88000
United States, AL Birmingham, AL, United States, 35233
United States, AZ Tucson, AZ, United States, 85719
United States, CA Burbank, CA, United States, 91505
United States, CA Oakland, CA, United States, 94611
United States, CA Roseville, CA, United States, 95661
United States, CA Sacramento, CA, United States, 95814
United States, CA San Francisco, CA, United States, 94115
United States, CA Santa Clara, CA, United States, 95051
United States, CA Vallejo, CA, United States, 94589
United States, CA Walnut Creek, CA, United States, 94596
United States, CT New Haven, CT, United States, 06511
United States, FL Sarasota, FL, United States, 34239
United States, GA Atlanta, GA, United States, 30322
United States, GA Gainesville, GA, United States, 30501
United States, GA Savannah, GA, United States, 31404
United States, IA Iowa City, IA, United States, 52242
United States, IL Chicago, IL, United States, 60637
United States, IL Chicago, IL, United States, 60612
United States, IL Hinsdale, IL, United States, 60521
United States, IN Indianapolis, IN, United States, 46260
United States, KY Lexington, KY, United States, 40536
United States, MD Baltimore, MD, United States, 21237
United States, MO St. Louis, MO, United States, 63110
United States, MS Jackson, MS, United States, 39216
United States, ND Fargo, ND, United States, 58122
United States, NE Omaha, NE, United States, 68114
United States, NH Lebanon, NH, United States, 03756
United States, NJ Camden, NJ, United States, 08103
United States, NJ Teaneck, NJ, United States, 07666
United States, NY Lake Success, NY, United States, 11042
United States, OH Centerville, OH, United States, 45459
United States, OH Cincinnati, OH, United States, 45242
United States, OH Columbus, OH, United States, 43214
United States, OH Hilliard, OH, United States, 43026
United States, RI Providence, RI, United States, 02905
United States, SD Sioux Falls, SD, United States, 57104
United States, TX Bedford, TX, United States, 76022
United States, TX Dallas, TX, United States, 75390
United States, TX Dallas, TX, United States, 75231
United States, TX Dallas, TX, United States, 75235
United States, TX Tyler, TX, United States, 75702
United States, VA Gainesville, VA, United States, 20155
United States, WI MILWAUKEE, WI, United States, 53226