| Trial Identifier: | 3475-811 |
| Sponsor: | MSD |
| Start Date: | October 2018 |
| Primary Completion Date: | March 2024 |
| Study Completion Date: | September 2025 |
For questions about your Trial Results Summary, please see Sponsor contact section within your Trial Results Summary.
| Language | Description |
| Protocol Plain Language Summary |
| Country | Location |
|---|---|
| Australia, New South Wales | Liverpool, New South Wales, Australia, 2170 |
| Australia, New South Wales | Westmead, New South Wales, Australia, 2145 |
| Australia, New South Wales | Wollongong, New South Wales, Australia, 2500 |
| Australia, Victoria | Clayton, Victoria, Australia, 3168 |
| Brazil, Bahia | Salvador, Bahia, Brazil, 41253-190 |
| Brazil, Ceara | Fortaleza, Ceara, Brazil, 60430-230 |
| Brazil, Parana | Curitiba, Parana, Brazil, 80810-050 |
| Brazil, Rio de Janeiro | Rio de Janeiro, Brazil, 20231-050 |
| Brazil, Rio Grande do Sul | Ijui, Rio Grande do Sul, Brazil, 98700 000 |
| Brazil, Rio Grande do Sul | Porto Alegre, Rio Grande do Sul, Brazil, 91350-200 |
| Brazil, Santa Catarina | Florianopolis, Santa Catarina, Brazil, 88034-000 |
| Brazil, Sao Paulo | Sao Paulo, Brazil, 03102-002 |
| Chile, Araucania | Temuco, Araucania, Chile, 4780000 |
| Chile, Maule | Talca, Maule, Chile, 3460000 |
| Chile, Region M. de Santiago | Santiago, Region M. de Santiago, Chile, 7500921 |
| Chile, Region M. de Santiago | Santiago, Region M. de Santiago, Chile, 8380455 |
| Chile, Region M. de Santiago | Santiago, Region M. de Santiago, Chile, 7620002 |
| China, Anhui | Shanghai, Anhui, China, 200080 |
| China, Beijing | Beijing, China, 100032 |
| China, Beijing | Beijing, China, 100142 |
| China, Beijing | Beijing, China, 100071 |
| China, Fujian | Fuzhou, Fujian, China, 350014 |
| China, Fujian | Fuzhou, Fujian, China, 350025 |
| China, Fujian | Xiamen, Fujian, China, 361003 |
| China, Guangdong | Guangzhou, Guangdong, China, 510080 |
| China, Heilongjiang | Harbin, Heilongjiang, China, 150081 |
| China, Henan | Zhengzhou, Henan, China, 450008 |
| China, Hunan | Changsha, Hunan, China, 410008 |
| China, Jiangsu | Nanjing, Jiangsu, China, 210009 |
| China, Jilin | Chang chun, Jilin, China, 130021 |
| China, Shanghai | Shanghai, China, 200032 |
| China, Xinjiang | Urumqi, Xinjiang, China, 830001 |
| China, Zhejiang | Hangzhou, Zhejiang, China, 310016 |
| China, Zhejiang | Hangzhou, Zhejiang, China, 310022 |
| China, Zhejiang | Hangzhou, Zhejiang, China, 310003 |
| France, Ain | Rouen, Ain, France, 76000 |
| France, Bas-Rhin | Strasbourg, Bas-Rhin, France, 67098 |
| France, Doubs | Besancon, Doubs, France, 25030 |
| France, Finistere | Brest, Finistere, France, 29200 |
| France, Nord | Lille, Nord, France, 59000 |
| France, Paris | Paris, France, 75012 |
| France, Rhone | Lyon, Rhone, France, 69008 |
| France, Val-de-Marne | Saint-Herblain, Val-de-Marne, France, 44805 |
| France, Val-de-Marne | Villejuif, Val-de-Marne, France, 94805 |
| Germany, Baden-Wurttemberg | Heilbronn, Baden-Wurttemberg, Germany, 74078 |
| Germany, Baden-Wurttemberg | Ludwigsburg, Baden-Wurttemberg, Germany |
| Germany, Baden-Wurttemberg | Tuebingen, Baden-Wurttemberg, Germany, 72076 |
| Germany, Bayern | Muenchen, Bayern, Germany, 81675 |
| Germany, Berlin | Berlin, Germany, 13353 |
| Germany, Bremen | Bremen, Germany, 28211 |
| Germany, Hamburg | Hamburg, Germany, 22763 |
| Germany, Hamburg | Hamburg, Germany, 20249 |
| Germany, Niedersachsen | Hannover, Niedersachsen, Germany, 30625 |
| Germany, Sachsen | Dresden, Sachsen, Germany, 01307 |
| Germany, Sachsen | Leipzig, Sachsen, Germany, 04103 |
| Guatemala, Guatemala | Guatemala, Guatemala, 01010 |
| Guatemala, Guatemala | Guatemala, Guatemala, 01015 |
| Guatemala, Guatemala | Guatemala, Guatemala, 01016 |
| Guatemala, Quetzaltenango | Quetzaltenango, Guatemala, 09001 |
| Ireland, Dublin | Dublin, Ireland, D09 V2N0 |
| Ireland, Dublin | Dublin, Ireland, D24 NR0A |
| Ireland, Dublin | Dublin, Ireland, D08NHY1 |
| Israel, N/A | Beer Sheva, N/A, Israel, 8410101 |
| Israel, N/A | Haifa, N/A, Israel, 3109601 |
| Israel, N/A | Holon, N/A, Israel, 5822012 |
| Israel, N/A | Jerusalem, N/A, Israel, 9112001 |
| Israel, N/A | Kfar-Saba, N/A, Israel, 4428132 |
| Israel, N/A | Petah Tikva, N/A, Israel, 4941492 |
| Israel, N/A | Ramat Gan, N/A, Israel, 5265601 |
| Israel, N/A | Tel Aviv, N/A, Israel, 6423906 |
| Italy, Bergamo | Bergamo, Italy, 24125 |
| Italy, Catanzaro | Catanzaro, Italy, 88100 |
| Italy, Milano | Milano, Italy, 20141 |
| Italy, Modena | Modena, Italy, 41124 |
| Italy, Napoli | Napoli, Italy, 80131 |
| Italy, Padova | Padova, Italy, 35128 |
| Italy, Pescara | Pescara, Italy, 65100 |
| Italy, Toscana | Pisa, Toscana, Italy, 56126 |
| Japan, Aichi | Nagoya, Aichi, Japan, 464-8681 |
| Japan, Chiba | Chiba, Japan, 260-8717 |
| Japan, Chiba | Kashiwa, Chiba, Japan, 277-8577 |
| Japan, Ehime | Matsuyama, Ehime, Japan, 791-0280 |
| Japan, Fukuoka | Fukuoka, Japan, 811-1395 |
| Japan, Gifu | Gifu, Japan, 501-1194 |
| Japan, Gunma | Ohta, Gunma, Japan, 373-8550 |
| Japan, Hiroshima | Hiroshima, Japan, 730-8518 |
| Japan, Hyogo | Akashi, Hyogo, Japan, 673-8558 |
| Japan, Hyogo | Kobe, Hyogo, Japan, 650-0047 |
| Japan, Ibaraki | Kasama, Ibaraki, Japan, 309-1793 |
| Japan, Kagawa | Kita-gun, Kagawa, Japan, 761-0793 |
| Japan, Kanagawa | Yokohama, Kanagawa, Japan, 241-8515 |
| Japan, Kumamoto | Kumamoto, Japan, 860-8556 |
| Japan, Miyagi | Osaki, Miyagi, Japan, 989-6183 |
| Japan, Niigata | Niigata, Japan, 951-8566 |
| Japan, Osaka | Hirakata, Osaka, Japan, 573-1191 |
| Japan, Osaka | Osaka, Japan, 541-8567 |
| Japan, Osaka | Osaka, Japan, 558-8558 |
| Japan, Osaka | Osaka, Japan, 540-0006 |
| Japan, Osaka | Osakasayama, Osaka, Japan, 589-8511 |
| Japan, Osaka | Suita, Osaka, Japan, 565-0871 |
| Japan, Saitama | Kitaadachi-gun, Saitama, Japan, 362-0806 |
| Japan, Shizuoka | Sunto-gun, Shizuoka, Japan, 411-8777 |
| Japan, Tochigi | Utsunomiya, Tochigi, Japan, 320-0834 |
| Japan, Tokyo | Mitaka, Tokyo, Japan, 181-8611 |
| Japan, Tokyo | Tokyo, Japan, 104-0045 |
| Japan, Tokyo | Tokyo, Japan, 113-8677 |
| Japan, Tokyo | Tokyo, Japan, 135-8550 |
| Japan, Tokyo | Tokyo, Japan, 105-8470 |
| Korea, Republic of, Seoul | Seoul, Korea, Republic of, 03722 |
| Korea, Republic of, Seoul | Seoul, Korea, Republic of, 06351 |
| Korea, Republic of, Seoul | Seoul, Korea, Republic of, 05505 |
| Korea, Republic of, Seoul | Seoul, Korea, Republic of, 03080 |
| New Zealand, Auckland | Auckland, New Zealand, 1023 |
| Poland, Dolnoslaskie | Wroclaw, Dolnoslaskie, Poland, 50-556 |
| Poland, Dolnoslaskie | Wroclaw, Dolnoslaskie, Poland, 53-413 |
| Poland, Lubelskie | Lublin, Lubelskie, Poland, 20-080 |
| Poland, Mazowieckie | Warszawa, Mazowieckie, Poland, 02-781 |
| Poland, Pomorskie | Gdynia, Pomorskie, Poland, 81-519 |
| Poland, Pomorskie | Koscierzyna, Pomorskie, Poland, 83-400 |
| Poland, Slaskie | Bielsko-Biala, Slaskie, Poland, 43-300 |
| Poland, Wielkopolskie | Konin, Wielkopolskie, Poland, 62-500 |
| Russian Federation, Baskortostan, Respublika | Ufa, Baskortostan, Respublika, Russian Federation, 450054 |
| Russian Federation, Chelyabinskaya oblast | Chelyabinsk, Chelyabinskaya oblast, Russian Federation, 454087 |
| Russian Federation, Moskovskaya oblast | Podolsk, Moskovskaya oblast, Russian Federation, 142110 |
| Russian Federation, Moskva | Moscow, Moskva, Russian Federation, 115478 |
| Russian Federation, Samarskaya oblast | Samara, Samarskaya oblast, Russian Federation, 443011 |
| Russian Federation, Sankt-Peterburg | Saint Petersburg, Sankt-Peterburg, Russian Federation, 198255 |
| Russian Federation, Sankt-Peterburg | Saint Petersburg, Sankt-Peterburg, Russian Federation, 197758 |
| Russian Federation, Sankt-Peterburg | Saint-Petersburg, Sankt-Peterburg, Russian Federation, 188663 |
| Spain, Alicante | Elche, Alicante, Spain, 03203 |
| Spain, Asturias | Oviedo, Asturias, Spain, 33011 |
| Spain, Barcelona | Badalona, Barcelona, Spain, 08916 |
| Spain, Barcelona | Barcelona, Spain, 08035 |
| Spain, Cantabria | Santander, Cantabria, Spain, 39008 |
| Spain, Madrid | Madrid, Spain, 28034 |
| Spain, Madrid | Pozuelo de Alarcon, Madrid, Spain, 28223 |
| Turkey, Adana | Adana, Turkey, 01370 |
| Turkey, Ankara | Ankara, Turkey, 06200 |
| Turkey, Ankara | Ankara, Turkey, 06100 |
| Turkey, Edirne | Edirne, Turkey, 22030 |
| Turkey, Erzurum | Erzurum, Turkey, 25240 |
| Turkey, Istanbul | Istanbul, Turkey, 34098 |
| Turkey, Izmir | Izmir, Turkey, 35340 |
| Turkey, Malatya | Malatya, Turkey, 44280 |
| Turkey, Sakarya | Sakarya, Turkey, 54290 |
| Ukraine, Dnipropetrovska oblast | Dnipro, Dnipropetrovska oblast, Ukraine, 49102 |
| Ukraine, Dnipropetrovska oblast | Kryviy Rih, Dnipropetrovska oblast, Ukraine, 50048 |
| Ukraine, Ivano-Frankivska oblast | Ivano-Frankivsk, Ivano-Frankivska oblast, Ukraine, 76018 |
| Ukraine, Kharkivska oblast | Kharkiv, Kharkivska oblast, Ukraine, 61070 |
| Ukraine, Kyiv | Kyiv, Ukraine, 03115 |
| Ukraine, Kyivska oblast | Khodosivka, Kyivska oblast, Ukraine, 08173 |
| Ukraine, Kyivska oblast | Kyiv, Kyivska oblast, Ukraine, 03022 |
| Ukraine, Kyivska oblast | Kyiv, Kyivska oblast, Ukraine, 03126 |
| Ukraine, Lvivska oblast | Lviv, Lvivska oblast, Ukraine, 79031 |
| Ukraine, Odeska oblast | Odesa, Odeska oblast, Ukraine, 65055 |
| Ukraine, Zaporizka oblast | Zaporizhzhya, Zaporizka oblast, Ukraine, 69104 |
| United Kingdom, Derbyshire | Derby, Derbyshire, United Kingdom, DE22 3NE |
| United Kingdom, Dundee City | Dundee, Dundee City, United Kingdom, DD1 9SY |
| United Kingdom, East Riding of Yorkshire | Cottingham, East Riding of Yorkshire, United Kingdom, HU16 5JQ |
| United Kingdom, London, City of | London, London, City of, United Kingdom, SW17 0QT |
| United Kingdom, London, City of | London, London, City of, United Kingdom, NW1 2PG |
| United Kingdom, Manchester | Manchester, United Kingdom, M20 4BX |
| United Kingdom, Surrey | Sutton, Surrey, United Kingdom, SM2 5PT |
| United Kingdom, United Kingdom | London, United Kingdom, United Kingdom, SW3 6JJ |
| United Kingdom, United Kingdom | Northwood, United Kingdom, United Kingdom, HA6 2RN |
| United Kingdom, Walsall | Walsall, United Kingdom, WS2 9PS |
| United States, CA | Los Angeles, CA, United States, 90095 |
| United States, CA | Monterey, CA, United States, 93940 |
| United States, CA | Orange, CA, United States, 92868 |
| United States, FL | Miami, FL, United States, 33136 |
| United States, GA | Newnan, GA, United States, 30265 |
| United States, IL | Zion, IL, United States, 60099 |
| United States, MA | Boston, MA, United States, 02215 |
| United States, MN | Minneapolis, MN, United States, 55404 |
| United States, MO | St. Louis, MO, United States, 63110 |
| United States, NC | Charlotte, NC, United States, 28204 |
| United States, NC | Durham, NC, United States, 27710 |
| United States, NJ | Middletown, NJ, United States, 07748 |
| United States, NY | New York, NY, United States, 10065 |
| United States, NY | Rochester, NY, United States, 14642 |
| United States, NY | West Harrison, NY, United States, 10604 |
| United States, OK | Tulsa, OK, United States, 74133 |
| United States, PA | Philadelphia, PA, United States, 19124 |
| United States, PA | Pittsburgh, PA, United States, 15212 |
| United States, SD | Sioux Falls, SD, United States, 57104 |
| United States, TX | Houston, TX, United States, 77030 |
| United States, VA | Roanoke, VA, United States, 24014 |
| United States, WA | Seattle, WA, United States, 98109 |
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