Efficacy and Safety of Lenvatinib (E7080/MK-7902) plus Pembrolizumab (MK-3475) plus Chemotherapy in Participants with Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-7902-015/E7080-G000-321/LEAP-015)

Trial Identifier: 7902-015
Sponsor: MSD
Collaborator:
Eisai
Start Date: December 2020
Primary Completion Date: October 2024
Study Completion Date: March 2026

Available Languages

For questions about your Trial Results Summary, please see Sponsor contact section within your Trial Results Summary.

Language Description
Protocol Plain Language Summary – English

Trial Locations

Country Location
Argentina, Buenos Aires Buenos Aires, Argentina, C1431FWO
Argentina, Buenos Aires Buenos Aires, Argentina, C1118AAT
Argentina, Buenos Aires Buenos Aires, Argentina, C1093AAS
Argentina, Buenos Aires Buenos Aires, Argentina, C1264AAA
Argentina, Buenos Aires Caba, Buenos Aires, Argentina, C1012AAR
Argentina, Buenos Aires Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina, C1426ANZ
Argentina, Cordoba Cordoba, Argentina, X5016KEH
Australia, New South Wales Kingswood, New South Wales, Australia, 2747
Australia, New South Wales Wollongong, New South Wales, Australia, 2500
Australia, Queensland Herston, Queensland, Australia, 4029
Australia, Western Australia Nedlands, Western Australia, Australia, 6009
Belgium, Namur Yvoir, Namur, Belgium, 5530
Belgium, Oost-Vlaanderen Gent, Oost-Vlaanderen, Belgium, 9000
Belgium, Vlaams-Brabant Leuven, Vlaams-Brabant, Belgium, 3000
Belgium, West-Vlaanderen Roeselare, West-Vlaanderen, Belgium, 8800
Canada, NS Halifax, NS, Canada, B3H 2Y9
Canada, ON Hamilton, ON, Canada, L8V 5C2
Canada, QC Sherbrooke, QC, Canada, J1H 5N4
Chile, Araucania Temuco, Araucania, Chile, Temuco
Chile, Coquimbo La Serena, Coquimbo, Chile, 1720430
Chile, Maule Talca, Maule, Chile, 3460000
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 8420383
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 7500836
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 7550000
China, Anhui Hefei, Anhui, China, 230001
China, Beijing Beijing, China, 100035
China, Beijing Beijing, China, 100021
China, Fujian Fuzhou, Fujian, China, 350014
China, Fujian Fuzhou, Fujian, China, 350025
China, Fujian Xiamen, Fujian, China, 361004
China, Fujian Xiamen, Fujian, China, 361003
China, Gansu Lanzhou, Gansu, China, 730000
China, Guangdong Guangzhou, Guangdong, China, 510000
China, Hainan Haikou, Hainan, China, 570102
China, Hebei Shijiazhuang, Hebei, China, 050011
China, Heilongjiang Harbin, Heilongjiang, China, 150081
China, Henan Zhengzhou, Henan, China, 450008
China, Hubei Wuhan, Hubei, China, 430079
China, Hunan Changsha, Hunan, China, 410006
China, Jiangsu changzhou, Jiangsu, China, 213000
China, Jiangsu Nanjing, Jiangsu, China, 210008
China, Jiangsu Nantong, Jiangsu, China, 226361
China, Jilin Changchun, Jilin, China, 130012
China, Shaanxi Xi An, Shaanxi, China, 710038
China, Shandong Linyi, Shandong, China, 276000
China, Shanghai Shanghai, China, 200120
China, Shanghai Shanghai, China, 200080
China, Tianjin Tianjin, China, 300060
China, Xinjiang Urumqi, Xinjiang, China, 830011
China, Zhejiang Hangzhou, Zhejiang, China, 310016
China, Zhejiang Hangzhou, Zhejiang, China, 310009
Colombia, Atlantico Barranquilla, Atlantico, Colombia, 080020
Colombia, Cesar Valledupar, Cesar, Colombia, 200001
Colombia, Cordoba Monteria, Cordoba, Colombia, 230002
Colombia, Distrito Capital de Bogota Bogota, Distrito Capital de Bogota, Colombia, 111321
Colombia, Narino Pasto, Narino, Colombia, 520001
Colombia, Risaralda Pereira, Risaralda, Colombia, 660001
Costa Rica, San Jose San José, San Jose, Costa Rica, 10103
Costa Rica, San Jose Santa Ana, San Jose, Costa Rica, 10903
France, Calvados Caen, Calvados, France, 14076
France, Cote-d Or Dijon, Cote-d Or, France, 21079
France, Gironde Pessac, Gironde, France, 33604
France, Haute-Savoie Epagny Metz-Tessy, Haute-Savoie, France, 74370
France, Paris Paris, France, 75012
France, Paris Paris, France, 75010
France, Pays-de-la-Loire Nantes, Pays-de-la-Loire, France, 44093
France, Rhone-Alpes Lyon, Rhone-Alpes, France, 69003
France, Val-de-Marne Creteil, Val-de-Marne, France, 94010
France, Vaucluse Avignon, Vaucluse, France, 84918
Germany, Bayern Muechen, Bayern, Germany, 81675
Germany, Bayern Regensburg, Bayern, Germany, 93053
Germany, Berlin Berlin, Germany, 13353
Germany, Hamburg Hamburg, Germany, 20249
Germany, Hessen Frankfurt am Main, Hessen, Germany, 60488
Germany, Niedersachsen Hannover, Niedersachsen, Germany, 30625
Germany, Sachsen Leipzig, Sachsen, Germany, 04103
Guatemala, Guatemala Guatemala, Guatemala, 01016
Guatemala, Guatemala Guatemala, Guatemala, 01010
Guatemala, Guatemala Guatemala, Guatemala, 01015
Hong Kong, N/A Hong Kong, N/A, Hong Kong, na
Hong Kong, N/A Hong Kong, N/A, Hong Kong, NA
Hong Kong, N/A Hong Kong, N/A, Hong Kong
Ireland, Dublin Dublin, Ireland, Dublin 9
Ireland, Leinster Dublin, Leinster, Ireland, Dublin 8
Israel, N/A Be'er Sheva, N/A, Israel, 8410101
Israel, N/A Hadera, N/A, Israel, 3810004
Israel, N/A Haifa, N/A, Israel, 3109601
Israel, N/A Jerusalem, N/A, Israel, 9112001
Israel, N/A Kfar-Saba, N/A, Israel, 4428164
Israel, N/A Petah Tikva, N/A, Israel, 4941492
Israel, N/A Tel Aviv, N/A, Israel, 6423906
Italy, Abruzzo Meldola, Abruzzo, Italy, 47014
Italy, Catanzaro Catanzaro, Italy, 88100
Italy, Friuli-Venezia Giulia Udine, Friuli-Venezia Giulia, Italy, 33100
Italy, Lombardia Milan, Lombardia, Italy, 20133
Italy, Lombardia Rozzano, Lombardia, Italy, 20089
Italy, Milano Milano, Italy, 20132
Italy, Napoli Napoli, Italy, 80131
Italy, Veneto Vicenza, Veneto, Italy, 36100
Japan, Aichi Nagoya, Aichi, Japan, 464-8681
Japan, Chiba Kashiwa, Chiba, Japan, 277-8577
Japan, Ehime Matsuyama, Ehime, Japan, 791-0280
Japan, Fukuoka Fukuoka, Japan, 811-1395
Japan, Hiroshima Hiroshima, Japan, 730-8518
Japan, Hyogo Akashi, Hyogo, Japan, 673-8558
Japan, Hyogo Kobe, Hyogo, Japan, 650-0047
Japan, Ibaraki Kasama, Ibaraki, Japan, 309-1793
Japan, Kagawa Kita-gun, Kagawa, Japan, 761-0793
Japan, Kanagawa Yokohama, Kanagawa, Japan, 241-8515
Japan, Osaka Hirakata, Osaka, Japan, 573-1191
Japan, Osaka Osaka, Japan, 5418567
Japan, Osaka Osakasayama, Osaka, Japan, 5898511
Japan, Saitama Kitaadachi-gun, Saitama, Japan, 362-0806
Japan, Tokyo Tokyo, Japan, 104-0045
Japan, Tokyo Tokyo, Japan, 135-8550
Korea, Republic of, Kyonggi-do Anyang-si, Kyonggi-do, Korea, Republic of, 14068
Korea, Republic of, Kyonggi-do Seongnam-si, Kyonggi-do, Korea, Republic of, 13620
Korea, Republic of, Seoul Seoul, Korea, Republic of, 03722
Korea, Republic of, Seoul Seoul, Korea, Republic of, 06273
Korea, Republic of, Seoul Seoul, Korea, Republic of, 06351
Korea, Republic of, Seoul Seoul, Korea, Republic of, 03080
Korea, Republic of, Seoul Seoul, Korea, Republic of, 08308
Korea, Republic of, Seoul Songpagu, Seoul, Korea, Republic of, 05505
Korea, Republic of, Taejon-Kwangyokshi Daejeon, Taejon-Kwangyokshi, Korea, Republic of, 35365
Poland, Dolnoslaskie Wroclaw, Dolnoslaskie, Poland, 53-413
Poland, Mazowieckie Warszawa, Mazowieckie, Poland, 02-034
Poland, Podkarpackie Przemysl, Podkarpackie, Poland, 37-700
Poland, Wielkopolskie Konin, Wielkopolskie, Poland, 62-500
Poland, Wielkopolskie Poznan, Wielkopolskie, Poland, 60-780
Russian Federation, Chelyabinskaya oblast Chelyabinsk, Chelyabinskaya oblast, Russian Federation, 454087
Russian Federation, Moskva Moscow, Moskva, Russian Federation, 121359
Russian Federation, Moskva Moscow, Moskva, Russian Federation, 105203
Russian Federation, Moskva Moscow, Moskva, Russian Federation, 115478
Russian Federation, Samarskaya oblast Samara, Samarskaya oblast, Russian Federation, 443011
Russian Federation, Sankt-Peterburg Saint Petersburg, Sankt-Peterburg, Russian Federation, 198255
Russian Federation, Sankt-Peterburg Saint-Petersburg, Sankt-Peterburg, Russian Federation, 197758
Russian Federation, Sankt-Peterburg Saint-Petersburg, Sankt-Peterburg, Russian Federation, 188663
Russian Federation, Yaroslavskaya oblast Yaroslavl, Yaroslavskaya oblast, Russian Federation, 150054
Spain, Asturias Oviedo, Asturias, Spain, 33011
Spain, Barcelona Barcelona, Spain, 08035
Spain, Cantabria Santander, Cantabria, Spain, 39008
Spain, Madrid Madrid, Spain, 28007
Taiwan, Province of China, Taichung Taichung, Taiwan, Province of China, 40447
Taiwan, Province of China, Tainan Tainan, Taiwan, Province of China, 704
Taiwan, Province of China, Taipei Taipei, Taiwan, Province of China, 10048
Taiwan, Province of China, Taoyuan Taoyuan, Taiwan, Province of China, 333
Turkey, Ankara Ankara, Turkey, 06100
Turkey, Ankara Ankara, Turkey, 06520
Turkey, Edirne Edirne, Turkey, 22030
Turkey, Erzurum Erzurum, Turkey, 25240
Turkey, Istanbul Istanbul, Turkey, 34098
Turkey, Istanbul Sakarya, Istanbul, Turkey, 54290
Turkey, Izmir Izmir, Turkey, 35040
United Kingdom, Cambridgeshire Cambridge, Cambridgeshire, United Kingdom, CB2 0QQ
United Kingdom, Dundee City Dundee, Dundee City, United Kingdom, DD1 9SY
United Kingdom, Glasgow City Glasgow, Glasgow City, United Kingdom, G12 0YN
United Kingdom, London, City of London, London, City of, United Kingdom, NW1 2BU
United Kingdom, London, City of London, London, City of, United Kingdom, SW3 6JJ
United Kingdom, Manchester Manchester, United Kingdom, M20 4BX
United Kingdom, Surrey Sutton, Surrey, United Kingdom, SM2 5PT
United Kingdom, Warwickshire Coventry, Warwickshire, United Kingdom, CV2 2DX
United States, CA Los Angeles, CA, United States, 90404
United States, DC Washington, DC, United States, 20007
United States, KY Louisville, KY, United States, 40202
United States, MA Boston, MA, United States, 02215
United States, MA Worcester, MA, United States, 01655
United States, MD Baltimore, MD, United States, 21224
United States, MI Detroit, MI, United States, 48202
United States, MI Grand Rapids, MI, United States, 49503
United States, MO St. Louis, MO, United States, 63110
United States, NY New York, NY, United States, 10029
United States, NY New York, NY, United States, 10065
United States, PA Pittsburgh, PA, United States, 15224